Staphylococcus aureus bloodstream infections in Latin America: results of a multinational prospective cohort study.

ABSTRACT: Background:Substantial heterogeneity in the epidemiology and management of Staphylococcus aureus bacteraemia (SAB) occurs in Latin America. We conducted a prospective cohort study in 24 hospitals from nine Latin American countries. Objectives:To assess the clinical impact of SAB in Latin America. Patients and methods:We evaluated differences in the 30?day attributable mortality among patients with SAB due to MRSA compared with MSSA involving 84?days of follow-up. Adjusted relative risks were calculated using a generalized linear model. Results:A total of 1030 patients were included. MRSA accounted for 44.7% of cases with a heterogeneous geographical distribution. MRSA infection was associated with higher 30?day attributable mortality [25% (78 of 312) versus 13.2% (48 of 363), adjusted RR: 1.94, 95% CI: 1.38-2.73, P?

SUBMITTER: Seas C 

PROVIDER: S-EPMC5890709 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature