CD29 is highly expressed on epithelial, myoepithelial, and mesenchymal stromal cells of human salivary glands.

ABSTRACT:

Objective

The phenotype of the cells present in the ductal region of salivary glands has been well characterized. However, it is imperative to identify novel biomarkers that can identify different cell types present in other glandular components for the development of therapeutic strategies and diagnostics of salivary gland disorders and malignancies. Our study aimed at the characterization of the expression and distribution of various cell surface markers, especially with a focus on CD29 in human fetal as well as adult glands.

Materials and methods

Paired human midgestation fetal and adult parotid, sublingual, and submandibular glands were collected. Phenotypic expression of various lineage-specific cell surface markers including CD29 was investigated in freshly collected g

SUBMITTER: Togarrati PP 

PROVIDER: S-EPMC5902634 | biostudies-literature | 2018 May

REPOSITORIES: biostudies-literature