Ontology highlight
ABSTRACT: Aim
Uterine transplantation (UTx) has been proposed as a treatment for permanent absolute uterine factor infertility. The study aims were to compare pulse oximetry and multispectral imaging (MSI), for intraoperative tracking of uterine oxygen saturation in animal UTx models (rabbit and sheep).Results/methodology
Imaging results confirmed the re-establishment of adequate perfusion in the transplanted organ after surgery. Comparison of oxygen saturation values between the pre-UTx donor and post-UTx recipient, and pre-UTx and post-UTx recipient reveals a statistically significant decrease in saturation levels post-UTx.Conclusion
The use of MSI is the first case in gynecology and has demonstrated promise of possible future human use. MSI technique has advantages over pulse oximetry - it provides spatial information in a real-time, noncontact manner.
SUBMITTER: Saso S
PROVIDER: S-EPMC5905613 | biostudies-literature | 2018 Apr
REPOSITORIES: biostudies-literature
Saso Srdjan S Clancy Neil T NT Jones Benjamin P BP Bracewell-Milnes Timothy T Al-Memar Maya M Cannon Eleanor M EM Ahluwalia Simran S Yazbek Joseph J Thum Meen-Yau MY Bourne Tom T Elson Daniel S DS Smith James Richard JR Ghaem-Maghami Sadaf S
Future science OA 20180206 4
<h4>Aim</h4>Uterine transplantation (UTx) has been proposed as a treatment for permanent absolute uterine factor infertility. The study aims were to compare pulse oximetry and multispectral imaging (MSI), for intraoperative tracking of uterine oxygen saturation in animal UTx models (rabbit and sheep).<h4>Results/methodology</h4>Imaging results confirmed the re-establishment of adequate perfusion in the transplanted organ after surgery. Comparison of oxygen saturation<i> </i>values between the pr ...[more]