Clock Gene Period in the Chagas Disease Vector Triatoma infestans (Hemiptera: Reduviidae).

ABSTRACT: To contribute to a better understanding of the molecular bases of the circadian biological rhythms in Chagas disease vectors, in this work we identified functional domains in the sequences of the clock protein PERIOD (PER) in Rhodnius prolixus and Triatoma infestans and analyzed the expression of the PER gene at mRNA level in T. infestans. The PER protein sequences comparison among these species and those from other insects revealed that the most similar regions are the PAS domains and the most variable is the COOH-terminal. On the other hand, the per gene expression in nervous tissue of adult T. infestans varies with a daily canonical rhythm in groups of individuals maintained under photoperiod (light/dark, LD) and constant dark (DD), showing a significant peak of expression at sunset. Th

SUBMITTER: Stroppa MM 

PROVIDER: S-EPMC5929179 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature