Ontology highlight
ABSTRACT:
SUBMITTER: Nobis S
PROVIDER: S-EPMC5940678 | biostudies-literature | 2018 May
REPOSITORIES: biostudies-literature
Scientific reports 20180508 1
Restrictive anorexia nervosa is associated with reduced eating and severe body weight loss leading to a cachectic state. Hypothalamus plays a major role in the regulation of food intake and energy homeostasis. In the present study, alterations of hypothalamic proteome and particularly of proteins involved in energy and mitochondrial metabolism have been observed in female activity-based anorexia (ABA) mice that exhibited a reduced food intake and a severe weight loss. In the hypothalamus, mitoch ...[more]