Ontology highlight
ABSTRACT:
SUBMITTER: Guo J
PROVIDER: S-EPMC5951811 | biostudies-literature | 2018 May
REPOSITORIES: biostudies-literature
Nature communications 20180514 1
There are mean differences in complex traits among global human populations. We hypothesize that part of the phenotypic differentiation is due to natural selection. To address this hypothesis, we assess the differentiation in allele frequencies of trait-associated SNPs among African, Eastern Asian, and European populations for ten complex traits using data of large sample size (up to ~405,000). We show that SNPs associated with height ([Formula: see text]), waist-to-hip ratio ([Formula: see text ...[more]