Effects of high-intensity interval training on fatigue and quality of life in testicular cancer survivors.

ABSTRACT:

Background

Testicular cancer survivors (TCS) are at increased risk of cancer-related fatigue (CRF), psychosocial impairment, and poor mental health-related quality of life (HRQoL). Here, we examine the effects of high-intensity interval training (HIIT) on patient-reported outcomes (PROs) in TCS. Secondarily, we explore cardiorespiratory fitness as a mediator of intervention effects and select baseline characteristics as moderators of intervention effects.

Methods

TCS (n = 63) were randomly assigned to 12 weeks of supervised HIIT or usual care (UC). PROs included CRF, depression, anxiety, stress, self-esteem, sleep quality, and HRQoL assessed at baseline, post-intervention, and 3-month follow-up.

Results

TCS (median 7 years postdiagnosis) completed 99% of training sess

SUBMITTER: Adams SC 

PROVIDER: S-EPMC5959855 | biostudies-literature | 2018 May

REPOSITORIES: biostudies-literature