GeneChip analysis of resistant Mycobacterium tuberculosis with previously treated tuberculosis in Changchun.

ABSTRACT:

Background

With the widespread use of rifampicin and isoniazid, bacterial resistance has become a growing problem. Additionally, the lack of relevant baseline information for the frequency of drug-resistant tuberculosis (TB) gene mutations is a critical issue, and the incidence of this infection in the city of Changchun has not investigated to date. However, compared with the slow traditional methods of drug susceptibility testing, recently developed detection methods, such as rifampicin and isoniazid resistance-related gene chip techniques, allow for rapid, easy detection and simultaneous testing for mutation frequency and drug resistance.

Methods

In this study, the rifampicin and isoniazid resistance-related gene mutation chip method was employed for an epidemiological inv

SUBMITTER: Zhang MJ 

PROVIDER: S-EPMC5964880 | biostudies-literature | 2018 May

REPOSITORIES: biostudies-literature