Do paternal semen parameters influence the birth weight or BMI of the offspring? A study from the Utah Population Database.

ABSTRACT: PURPOSE:To study the role of individual semen parameters on the offspring birth weight and body mass index (BMI) from a population of men evaluated in an assisted reproduction technology (ART) clinic compared to fertile controls. METHODS:We performed a retrospective study using a cohort with fertile, age-matched controls of men evaluated with semen analysis at the University of Utah Andrology Clinic from 1996 to 2011 and Intermountain Healthcare from 2002 to 2011. We use the offspring from both our sub-fertile cohort and controls using the Utah Population Database. The two main outcomes of interest were offspring birth weight and adolescent BMI. RESULTS:The offspring of men with impaired sperm parameters had significantly lower birth weight compared to fertile control offspring. Low-concen

SUBMITTER: Anderson RE 

PROVIDER: S-EPMC5984892 | biostudies-literature | 2018 May

REPOSITORIES: biostudies-literature