HIV treatment is associated with a two-fold higher probability of raised triglycerides: Pooled Analyses in 21 023 individuals in sub-Saharan Africa.
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ABSTRACT:
SUBMITTER: Ekoru K
PROVIDER: S-EPMC5985947 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
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HIV treatment is associated with a two-fold higher probability of raised triglycerides: Pooled Analyses in 21 023 individuals in sub-Saharan Africa.
Ekoru Kenneth K Young Elizabeth H EH Dillon David G DG Gurdasani Deepti D Stehouwer Nathan N Faurholt-Jepsen Daniel D Levitt Naomi S NS Crowther Nigel J NJ Nyirenda Moffat M Njelekela Marina A MA Ramaiya Kaushik K Nyan Ousman O Adewole Olanisun O OO Anastos Kathryn K Compostella Caterina C Dave Joel A JA Fourie Carla M CM Friis Henrik H Kruger Iolanthe M IM Longenecker Chris T CT Maher Dermot P DP Mutimura Eugene E Ndhlovu Chiratidzo E CE Praygod George G Pefura Yone Eric W EW Pujades-Rodriguez Mar M Range Nyagosya N Sani Mahmoud U MU Sanusi Muhammad M Schutte Aletta E AE Sliwa Karen K Tien Phyllis C PC Vorster Este H EH Walsh Corinna C Gareta Dickman D Mashili Fredirick F Sobngwi Eugene E Adebamowo Clement C Kamali Anatoli A Seeley Janet J Smeeth Liam L Pillay Deenan D Motala Ayesha A AA Kaleebu Pontiano P Sandhu Manjinder S MS
Global health, epidemiology and genomics 20180508
<h4>Background</h4>Anti-retroviral therapy (ART) regimes for HIV are associated with raised levels of circulating triglycerides (TG) in western populations. However, there are limited data on the impact of ART on cardiometabolic risk in sub-Saharan African (SSA) populations.<h4>Methods</h4>Pooled analyses of 14 studies comprising 21 023 individuals, on whom relevant cardiometabolic risk factors (including TG), HIV and ART status were assessed between 2003 and 2014, in SSA. The association betwee ...[more]
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