Validation of prediction models for risk stratification of incidentally detected pulmonary subsolid nodules: a retrospective cohort study in a Korean tertiary medical centre.

ABSTRACT:

Objectives

To validate the performances of two prediction models (Brock and Lee models) for the differentiation of minimally invasive adenocarcinoma (MIA) and invasive pulmonary adenocarcinoma (IPA) from preinvasive lesions among subsolid nodules (SSNs).

Design

A retrospective cohort study.

Setting

A tertiary university hospital in South Korea.

Participants

410 patients with 410 incidentally detected SSNs who underwent surgical resection for the pulmonary adenocarcinoma spectrum between 2011 and 2015.

Primary and secondary outcome measures

Using clinical and radiological variables, the predicted probability of MIA/IPA was calculated from pre-existing logistic models (Brock and Lee models). Areas under the receiver operating characteristic curve (AUCs) we

SUBMITTER: Kim H 

PROVIDER: S-EPMC5988095 | biostudies-literature | 2018 May

REPOSITORIES: biostudies-literature