Obesity may be erythropoietin dose-saving in hemodialysis patients.

ABSTRACT:

Background

In dialysis patients, the obesity-survival paradox still requires an explanation. Anemia and high doses of erythropoiesis-stimulating agents (ESAs) are associated with worse outcomes in the hemodialysis (HD) population. In the present study, we explored the relation between obesity and anemia control in a sample of maintenance HD patients in Egypt.

Methods

This multicenter observational study included 733 patients on maintenance HD from 9 hemodialysis centers in Egypt. Clinical and laboratory data as well as average doses of ESAs and parenteral iron were recorded. The erythropoietin resistance index (ERI) was calculated.

Results

Obesity, defined as a body mass index (BMI) ≥ 30 kg/m², was present in 22.6% of the studied population. The target hemo

SUBMITTER: El-Kannishy GM 

PROVIDER: S-EPMC6027808 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature