Maternal consumption of green tea extract during pregnancy and lactation alters offspring's metabolism in rats.

ABSTRACT:

Introduction

Green tea extract has anti-inflammatory and antioxidant effects which improve dyslipidemia and decrease adipose tissue depots associated with hyperlipidic diet consumption.

Objective

To evaluate the effect of green tea extract consumption by rats during pregnancy and lactation on the metabolism of their offspring that received control or high-fat diet with water during 10 weeks after weaning.

Methods

Wistar rats received water (W) or green tea extract diluted in water (G) (400 mg/kg body weight/day), and control diet (10 animals in W and G groups) during pregnancy and lactation. After weaning, offspring received water and a control (CW) or a high-fat diet (HW), for 10 weeks. One week before the end of treatment, oral glucose tolerance test was performed.

SUBMITTER: Hachul ACL 

PROVIDER: S-EPMC6051583 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature