Ontology highlight
ABSTRACT:
SUBMITTER: Lencioni R
PROVIDER: S-EPMC6095431 | biostudies-literature | 2016 Aug
REPOSITORIES: biostudies-literature
Lencioni Riccardo R Cioni Dania D
Hepatic oncology 20160610 3
When heated during a radiofrequency ablation (RFA) procedure to ≥40°C, lyso-thermosensitive liposomal doxorubicin (LTLD) produces high drug concentration in the surrounding margins of the ablation zone. The hypothesis that the RFA + LTLD combination can effectively treat hepatocellular carcinoma (HCC) was investigated in the HEAT study: adding LTLD did not improve the efficacy of normal practice RFA. However, among the 285 patients with a solitary lesion who received at least 45-min RFA dwell ti ...[more]