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Interactive effects of age and respiratory virus on severe lower respiratory infection.

ABSTRACT: We investigated risk factors for severe acute lower respiratory infections (ALRI) among hospitalised children 8 months were at greater risk from influenza-associated ICU admissions and long hospital stay. Children with ADV had increased LOS across all ages. In the first 2 years of life, the effects of different viruses on ALRI severity varies with age. Our findings help to identify specific ages that would most benefit from virus-specific interventions such as vaccines and antivirals.

SUBMITTER: Prasad N 

PROVIDER: S-EPMC6135664 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature

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Interactive effects of age and respiratory virus on severe lower respiratory infection.

Prasad N N   Trenholme A A AA   Huang Q S QS   Thompson M G MG   Pierse N N   Widdowson M A MA   Wood T T   Seeds R R   Taylor S S   Grant C C CC   Newbern E C EC  

Epidemiology and infection 20180726 14

We investigated risk factors for severe acute lower respiratory infections (ALRI) among hospitalised children 8 months were at greater risk from influenza-associated ICU admissions and long hospital stay. Children with ADV had increased LOS across all ages. In the first 2 years of life, the effects of different viruses on ALRI severity varies with age. Our findings help to identify specific ages that would most benefit from virus-specific interventions such as vaccines and antivirals. ...[more]

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