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Interactive effects of age and respiratory virus on severe lower respiratory infection.

ABSTRACT: We investigated risk factors for severe acute lower respiratory infections (ALRI) among hospitalised children 8 months were at greater risk from influenza-associated ICU admissions and long hospital stay. Children with ADV had increased LOS across all ages. In the first 2 years of life, the effects of different viruses on ALRI severity varies with age. Our findings help to identify specific ages that would most benefit from virus-specific interventions such as vaccines and antivirals.

SUBMITTER: Prasad N

PROVIDER: S-EPMC6135664 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature

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Interactive effects of age and respiratory virus on severe lower respiratory infection.

Prasad N N Trenholme A A AA Huang Q S QS Thompson M G MG Pierse N N Widdowson M A MA Wood T T Seeds R R Taylor S S Grant C C CC Newbern E C EC

Epidemiology and infection 20180726 14

We investigated risk factors for severe acute lower respiratory infections (ALRI) among hospitalised children 8 months were at greater risk from influenza-associated ICU admissions and long hospital stay. Children with ADV had increased LOS across all ages. In the first 2 years of life, the effects of different viruses on ALRI severity varies with age. Our findings help to identify specific ages that would most benefit from virus-specific interventions such as vaccines and antivirals. ...[more]

PMID: 30047350

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