Three-dimensional free breathing whole heart cardiovascular magnetic resonance T₁ mapping at 3 T.

ABSTRACT:

Background

This study demonstrates a three-dimensional (3D) free-breathing native myocardial T₁ mapping sequence at 3 T.

Methods

The proposed sequence acquires three differently T₁-weighted volumes. The first two volumes receive a saturation pre-pulse with different recovery time. The third volume is acquired without magnetization preparation and after a significant recovery time. Respiratory navigator gating and volume-interleaved acquisition are adopted to mitigate misregistration. The proposed sequence was validated through simulation, phantom experiments and in vivo experiments in 12 healthy adult subjects.

Results

In phantoms, good agreement on T₁ measurement was achieved between the proposed sequence and the reference inversion r

SUBMITTER: Guo R 

PROVIDER: S-EPMC6139904 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature