Pre- and post-natal macronutrient supplementation for HIV-positive women in Tanzania: Effects on infant birth weight and HIV transmission.

ABSTRACT:

Objective

To determine if a protein-calorie supplement (PCS) plus a micronutrient supplement (MNS) improves outcomes for HIV-infected lactating women and their infants.

Design

Randomized, controlled trial.

Setting

Dar es Salaam, Tanzania.

Subjects, participants

Pregnant HIV-infected women enrolled in PMTCT programs who intended to breastfeed for 6 months.

Intervention

Randomization 1:1 to administration of a PCS plus MNS versus MNS alone among 96 eligible women beginning in the third trimester and continuing for 6 months of breast-feeding.

Main outcome measure(s)

Primary: infant weight at 3 months. Secondary: maternal BMI at 6 months.

Results

PCS resulted in significant increases in daily energy intake compared to MNS at all time points (ra

SUBMITTER: Magohe A 

PROVIDER: S-EPMC6181269 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature