Development and validation of the PEPPER framework (Prenatal Exposure PubMed ParsER) with applications to food additives.

ABSTRACT:

Background

Globally, 36% of deaths among children can be attributed to environmental factors. However, no comprehensive list of environmental exposures exists. We seek to address this gap by developing a literature-mining algorithm to catalog prenatal environmental exposures.

Methods

We designed a framework called.

Pepper

Prenatal Exposure PubMed ParsER to a) catalog prenatal exposures studied in the literature and b) identify study type. Using PubMed Central, PEPPER classifies article type (methodology, systematic review) and catalogs prenatal exposures. We coupled PEPPER with the FDA's food additive database to form a master set of exposures.

Results

We found that of 31 764 prenatal exposure studies only 53.0% were methodology studies. PEPPER consists of 219

SUBMITTER: Boland MR 

PROVIDER: S-EPMC6213088 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature