Fluoride-doped amorphous calcium phosphate nanoparticles as a promising biomimetic material for dental remineralization.

ABSTRACT: Demineralization of dental hard tissue is a widespread problem and the main responsible for dental caries and dentin hypersensitivity. The most promising strategies to induce the precipitation of new mineral phase are the application of materials releasing gradually Ca²⁺ and PO₄^3- ions or mimicking the mineral phase of the host tissue. However, the design of formulations covering both processes is so far a challenge in preventive dentistry. In this work, we have synthesized innovative biomimetic amorphous calcium phosphate (ACP), which has been, for the first time, doped with fluoride ions (FACP) to obtain materials with enhanced anti-caries and remineralizing properties. Significantly, the doping with fluoride (F) did not vary the physico-chemical features

SUBMITTER: Iafisco M 

PROVIDER: S-EPMC6242929 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature