Neutrophil Lymphocyte Ratio and Cardiovascular Disease Risk: A Systematic Review and Meta-Analysis.

ABSTRACT:

Objective

This systematic review aimed to measure the association between neutrophil lymphocyte ratio (NLR) and cardiovascular disease (CVD) risk.

Methods

Relevant studies were identified from Medline and Scopus databases. Observational studies with NLR as a study factor were eligible for review. The outcomes of interest were any type of CVD including acute coronary syndrome, coronary artery disease, stroke, or a composite of these cardiovascular events. Mean differences in NLR between CVD and non-CVD patients were pooled using unstandardized mean difference (USMD). Odds ratios of CVD between high and low NLR groups were pooled using a random effects model.

Results

Thirty-eight studies (n=76,002) were included. High NLR was significantly associated with the risks of C

SUBMITTER: Angkananard T 

PROVIDER: S-EPMC6252240 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature