Hepatitis C virus infection and the risk of cancer among elderly US adults: A registry-based case-control study.

ABSTRACT:

Background

Hepatitis C virus (HCV) infection causes hepatocellular carcinoma (HCC) and subtypes of non-Hodgkin lymphoma (NHL). Associations with other cancers are not established. The authors systematically assessed associations between HCV infection and cancers in the US elderly population.

Methods

This was a registry-based case-control study using Surveillance, Epidemiology, and End Results (SEER)-Medicare data in US adults aged ≥66 years. Cases (n = 1,623,538) were patients who had first cancers identified in SEER registries (1993-2011). Controls (n = 200,000) were randomly selected, cancer-free individuals who were frequency-matched to cases on age, sex, race, and calendar year. Associations with HCV (documented by Medicare claims) were determined using logistic regressi

SUBMITTER: Mahale P 

PROVIDER: S-EPMC6295146 | biostudies-literature | 2017 Apr

REPOSITORIES: biostudies-literature