Spontaneous Breathing in Early Acute Respiratory Distress Syndrome: Insights From the Large Observational Study to UNderstand the Global Impact of Severe Acute Respiratory FailurE Study.

ABSTRACT:

Objectives

To describe the characteristics and outcomes of patients with acute respiratory distress syndrome with or without spontaneous breathing and to investigate whether the effects of spontaneous breathing on outcome depend on acute respiratory distress syndrome severity.

Design

Planned secondary analysis of a prospective, observational, multicentre cohort study.

Setting

International sample of 459 ICUs from 50 countries.

Patients

Patients with acute respiratory distress syndrome and at least 2 days of invasive mechanical ventilation and available data for the mode of mechanical ventilation and respiratory rate for the 2 first days.

Interventions

Analysis of patients with and without spontaneous breathing, defined by the mode of mechanical ventilati

SUBMITTER: van Haren F 

PROVIDER: S-EPMC6336491 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature