Unknown

Dataset Information

0

Surfactant status and respiratory outcome in premature infants receiving late surfactant treatment.

ABSTRACT: BACKGROUND:Many premature infants with respiratory failure are deficient in surfactant, but the relationship to occurrence of bronchopulmonary dysplasia (BPD) is uncertain. METHODS:Tracheal aspirates were collected from 209 treated and control infants enrolled at 7-14 days in the Trial of Late Surfactant. The content of phospholipid, surfactant protein B, and total protein were determined in large aggregate (active) surfactant. RESULTS:At 24?h, surfactant treatment transiently increased surfactant protein B content (70%, p?

SUBMITTER: Ballard PL 

PROVIDER: S-EPMC6377352 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature

Json Xml
altmetric image

Publications

Surfactant status and respiratory outcome in premature infants receiving late surfactant treatment.

Ballard Philip L PL   Keller Roberta L RL   Truog William E WE   Chapin Cheryl C   Horneman Hart H   Segal Mark R MR   Ballard Roberta A RA  

Pediatric research 20180815 3

<h4>Background</h4>Many premature infants with respiratory failure are deficient in surfactant, but the relationship to occurrence of bronchopulmonary dysplasia (BPD) is uncertain.<h4>Methods</h4>Tracheal aspirates were collected from 209 treated and control infants enrolled at 7-14 days in the Trial of Late Surfactant. The content of phospholipid, surfactant protein B, and total protein were determined in large aggregate (active) surfactant.<h4>Results</h4>At 24 h, surfactant treatment transien  ...[more]

Similar Datasets

Unknown Randomized Trial of Late Surfactant Treatment in Ventilated Preterm Infants Receiving Inhaled Nitric Oxide.
| S-EPMC4698022 | biostudies-literature
Unknown Surfactant proteins gene variants in premature newborn infants with severe respiratory distress syndrome.
| S-EPMC5953905 | biostudies-literature
Proteomics Composition and origin of lung fluid proteome in premature infants and relationship to respiratory outcome
2020-11-23 | PXD021966 | Pride
Unknown Prophylactic administration of surfactant in extremely premature infants.
| S-EPMC2951078 | biostudies-other
Unknown Pulmonary Vascular Disease in Premature Infants. Early Predictive Models of Late Respiratory Morbidity.
| S-EPMC6467304 | biostudies-literature
Unknown A multicenter, randomized, double-blind trial of a new porcine surfactant in premature infants with respiratory distress syndrome.
| S-EPMC4879903 | biostudies-literature
Unknown Composition and origin of lung fluid proteome in premature infants and relationship to respiratory outcome.
| S-EPMC7728257 | biostudies-literature
Unknown Risk scoring tool to predict respiratory syncytial virus hospitalisation in premature infants.
| S-EPMC6099524 | biostudies-literature
Unknown Late Diagnosis of Infants with PCD and Neonatal Respiratory Distress.
| S-EPMC7563976 | biostudies-literature
Unknown Late-Onset Bloodstream Infection and Perturbed Maturation of the Gastrointestinal Microbiota in Premature Infants.
| S-EPMC4500406 | biostudies-literature