Elucidating bidirectional relationship between metabolic syndrome and elevated faecal haemoglobin concentration: a Taiwanese community-based cohort study.

ABSTRACT:

Objectives

To elucidate the bidirectional temporal relationship between elevated faecal haemoglobin (f-Hb) concentration and metabolic syndrome (MetS).

Design

A longitudinal cohort study was conducted by utilising data on community-based periodical screening for colorectal cancer with faecal immunochemical test (FIT) and health check-up for MetS.

Setting

Population-based organised integrated service screening in Keelung city, Taiwan.

Participants

We enrolled a total of 62,293 community residents aged 40-79 years.

Main outcomes and measures

Bidirectional outcomes of FIT-positive and MetS were measured.

Results

The presence of MetS at baseline led to a statistically significant 31% elevated risk of being incident FIT-positive (adjusted HR, (aHR)=1.3

SUBMITTER: Ku MS 

PROVIDER: S-EPMC6429718 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature