Vitamin D3 supplementation (4000 IU/d for 1 y) eliminates differences in circulating 25-hydroxyvitamin D between African American and white men.

ABSTRACT:

Background

African Americans suffer disproportionately from diabetes and cardiovascular disease and are significantly more likely to have suboptimal concentrations of circulating 25-hydroxyvitamin D [25(OH)D]. The results of epidemiologic and observational studies suggest that there is a link between vitamin D deficiency and the risk of cardiometabolic disorders, which underscores the importance of maintaining healthy concentrations of 25(OH)D.

Objective

The objective was to investigate whether daily supplementation with 4000 IU vitamin D(3) for 1 y would eliminate any disparities in circulating concentrations of 25(OH)D between African American and white men.

Design

Serum concentrations of 25(OH)D were measured every 2 mo in 47 subjects who received a daily oral dose

SUBMITTER: Garrett-Mayer E 

PROVIDER: S-EPMC6443291 | biostudies-literature | 2012 Aug

REPOSITORIES: biostudies-literature