Optimization of spray drying parameters and food additives to reduce glycation using response surface methodology in powdered infant formulas.

ABSTRACT: The heat-based spray drying process generating the highest level of advanced glycation end-products (AGEs) in the infant formula processing was set as a control point from which the levels of AGE markers, N-carboxymethyllysine, 5-hydroxymethylfurfural, and fluorescence intensity, can be mitigated. We optimized the parameters, including inlet temperature, feeding rate, and aspirator rate during spray drying, and alternatively optimized food additives, including pyridoxine hydrochloride, dl-α-tocopheryl acetate, and l-carnitine. Using response surface methodology, the optimal condition based on our experimental condition for the inlet temperature, pump rate, and aspirator rate were 148.7 °C, 342.4 mL/h and 28.6 m³/h, respectively, and the optimal conditions of pyridoxine hy

SUBMITTER: Lee HM 

PROVIDER: S-EPMC6484099 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature