Validity of the Seattle Heart Failure Model after heart failure hospitalization.

ABSTRACT:

Aims

Heart failure hospitalization is a sentinel event associated with increased mortality risk. Whether long-term heart failure risk models such as the Seattle Heart Failure Model (SHFM) accurately assess risk in the post-hospital setting is unknown.

Methods and results

The SHFM was applied to a cohort of 2242 consecutive patients (50% women; mean age 73) on discharge after acute heart failure hospitalization and analysed for the primary endpoint of all-cause mortality. Model discrimination and calibration were assessed. Direct patient-level comparison between our study cohort and the original SHFM cohorts was also performed to confirm and quantify the degree and extent of increased mortality risk attributable to post-hospital status. The SHFM demonstrated good overall risk

SUBMITTER: Li S 

PROVIDER: S-EPMC6487734 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature