Influenza and associated co-infections in critically ill immunosuppressed patients.

ABSTRACT:

Background

It is unclear whether influenza infection and associated co-infection are associated with patient-important outcomes in critically ill immunocompromised patients with acute respiratory failure.

Methods

Preplanned secondary analysis of EFRAIM, a prospective cohort study of 68 hospitals in 16 countries. We included 1611 patients aged 18 years or older with non-AIDS-related immunocompromise, who were admitted to the ICU with acute hypoxemic respiratory failure. The main exposure of interest was influenza infection status. The primary outcome of interest was all-cause hospital mortality, and secondary outcomes ICU length of stay (LOS) and 90-day mortality.

Results

Influenza infection status was categorized into four groups: patients with influenza alone (n = 95

SUBMITTER: Martin-Loeches I 

PROVIDER: S-EPMC6498695 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature