MetaOmics: analysis pipeline and browser-based software suite for transcriptomic meta-analysis.

ABSTRACT:

Summary

The rapid advances of omics technologies have generated abundant genomic data in public repositories and effective analytical approaches are critical to fully decipher biological knowledge inside these data. Meta-analysis combines multiple studies of a related hypothesis to improve statistical power, accuracy and reproducibility beyond individual study analysis. To date, many transcriptomic meta-analysis methods have been developed, yet few thoughtful guidelines exist. Here, we introduce a comprehensive analytical pipeline and browser-based software suite, called MetaOmics, to meta-analyze multiple transcriptomic studies for various biological purposes, including quality control, differential expression analysis, pathway enrichment analysis, differential co-expression netwo

SUBMITTER: Ma T 

PROVIDER: S-EPMC6499246 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature