Omega-3 intake is associated with attenuated inflammatory response and cardiac remodeling after myocardial infarction.

ABSTRACT:

Background

Myocardial infarction (MI) elicits an intense acute inflammatory response that is essential for cardiac repair. However, an excessive inflammatory response also favors myocardial apoptosis, cardiac remodeling, and cardiovascular mortality. Omega-3 polyunsaturated fatty acids (ω-3) bear anti-inflammatory effects, which may mitigate the inflammatory response during MI. This study investigated whether ω-3 intake is associated with attenuation of the MI-related inflammatory response and cardiac remodeling.

Methods

ST-elevation MI (STEMI) patients (n = 421) underwent clinical, biochemical, nutritional, 3D echocardiogram, Cardiac Magnetic Resonance imaging (CMRi) at 30 days and 3D echocardiogram imaging at six months after the MI. Blood tests were performed at day one (

SUBMITTER: Campos-Staffico AM 

PROVIDER: S-EPMC6503367 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature