Mu-opioid antagonists for opioid-induced bowel dysfunction in people with cancer and people receiving palliative care.
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ABSTRACT:
SUBMITTER: Candy B
PROVIDER: S-EPMC6513061 | biostudies-literature | 2018 Jun
REPOSITORIES: biostudies-literature
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Mu-opioid antagonists for opioid-induced bowel dysfunction in people with cancer and people receiving palliative care.
Candy Bridget B Jones Louise L Vickerstaff Victoria V Larkin Philip J PJ Stone Patrick P
The Cochrane database of systematic reviews 20180605
<h4>Background</h4>Opioid-induced bowel dysfunction (OIBD) is characterised by constipation, incomplete evacuation, bloating, and gastric reflux. It is one of the major adverse events of treatment for pain in cancer and in palliative care, resulting in increased morbidity and reduced quality of life.This is an update of two Cochrane reviews. One was published in 2011, Issue 1 on laxatives and methylnaltrexone for the management of constipation in people receiving palliative care; this was update ...[more]
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