Dataset Information
Ukbtools: An R package to manage and query UK Biobank data.
Ontology highlight
ABSTRACT: Introduction
The UK Biobank (UKB) is a resource that includes detailed health-related data on about 500,000 individuals and is available to the research community. However, several obstacles limit immediate analysis of the data: data files vary in format, may be very large, and have numerical codes for column names.Results
ukbtools removes all the upfront data wrangling required to get a single dataset for statistical analysis. All associated data files are merged into a single dataset with descriptive column names. The package also provides tools to assist in quality control by exploring the primary demographics of subsets of participants; query of disease diagnoses for one or more individuals, and estimating disease frequency relative to a reference variable; and to retrieve genetic metadata.Conclusion
Having a dataset with meaningful variable names, a set of UKB-specific exploratory data analysis tools, disease query functions, and a set of helper functions to explore and write genetic metadata to file, will rapidly enable UKB users to undertake their research.
SUBMITTER: Hanscombe KB
PROVIDER: S-EPMC6544205 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Publications
ukbtools: An R package to manage and query UK Biobank data.
PloS one 20190531 5
<h4>Introduction</h4>The UK Biobank (UKB) is a resource that includes detailed health-related data on about 500,000 individuals and is available to the research community. However, several obstacles limit immediate analysis of the data: data files vary in format, may be very large, and have numerical codes for column names.<h4>Results</h4>ukbtools removes all the upfront data wrangling required to get a single dataset for statistical analysis. All associated data files are merged into a single d ...[more]