Menopausal status is associated with a high risk for residual disease after cervical conization with positive margins.

ABSTRACT:

Background

We aimed to determine demographic and clinicopathological predictors for residual disease in women with cervical intraepithelial neoplasia (CIN 2/3) with endocervical cone margin involvement.

Methods and findings

A cross-sectional study was conducted. The eligible patients were women who underwent hysterectomy as a treatment option after having a positive endocervical margin for CIN 2/3 in cervix conization specimens from 2000 to 2015. The patients were divided into two groups based on the persistence of CIN 2/3 and absence of CIN 2/3 in hysterectomy specimens. Demographic, clinical and histology information were collected in both groups. A total of 80 patients were eligible for the study; 37 (46.3%) had no persistence of CIN 2/3 and 43 (53.7%) had persistence of

SUBMITTER: Bilibio JP 

PROVIDER: S-EPMC6548378 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature