Inhibitory effects of Azadirachta indica secondary metabolites formulated cosmetics on some infectious pathogens and oxidative stress radicals.

ABSTRACT:

Background

Infectious diseases, particularly those due to multi-drug resistant bacterial strains are almost impossible to cure globally. In this study we investigated the inhibitory effects of Azadirachta indica A. Juss secondary metabolites (AISM) formulated soap and cream for management of infectious and oxidative stress-related diseases (OSD).

Methods

The antibacterial, radical scavenging and cytotoxic effects of the neem cosmetics were examined by serial dilution, spectrophotometric and hemolytic techniques respectively, while the AISM in the essential oils (EOs) were elucidated by Gas chromatography-mass spectrometry (GC-MS) and retention index.

Results

The neem cosmetics without AISM exhibited bacteriostatic effects against five reference bacterial strains (Stap

SUBMITTER: Okoh SO 

PROVIDER: S-EPMC6558881 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature