Reproductive toxicity of fluoroquinolones in birds.

ABSTRACT:

Background

While commercial poultry and captive birds are exposed to antimicrobials through direct medication, environmental pollution may result in contamination of wild birds. Fluoroquinolones are commonly used medications to treat severe avian bacterial infections; however, their adverse effects on birds remain understudied. Here, we examine toxicity of enrofloxacin and marbofloxacin during the egg incubation period using the chicken (Gallus Gallus domesticus) as a model avian species. Laboratory tests were based on eggs injected with 1, 10 and 100 μg of fluoroquinolones per 1 g of egg weight prior to the start of incubation and monitoring of chick blood biochemistry, reproductive parameters and heart rate during incubation.

Results

Eggs treated with fluoroquinolones disp

SUBMITTER: Hruba H 

PROVIDER: S-EPMC6588855 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature