Ontology highlight
ABSTRACT:
SUBMITTER: Oetting WS
PROVIDER: S-EPMC6597284 | biostudies-literature | 2019 Jun
REPOSITORIES: biostudies-literature
Oetting William S WS Wu Baolin B Schladt David P DP Guan Weihua W van Setten Jessica J Keating Brendan J BJ Iklé David D Remmel Rory P RP Dorr Casey R CR Mannon Roslyn B RB Matas Arthur J AJ Israni Ajay K AK Jacobson Pamala A PA
Transplantation 20190601 6
<h4>Background</h4>The immunosuppressants tacrolimus and mycophenolate are important components to the success of organ transplantation, but are also associated with adverse effects, such as nephrotoxicity, anemia, leukopenia, and new-onset diabetes after transplantation. In this report, we attempted to identify genetic variants which are associated with these adverse outcomes.<h4>Methods</h4>We performed a genome-wide association study, using a genotyping array tailored specifically for transpl ...[more]