Ontology highlight
ABSTRACT:
SUBMITTER: Leth JM
PROVIDER: S-EPMC6600238 | biostudies-literature | 2019 Jun
REPOSITORIES: biostudies-literature
International journal of molecular sciences 20190605 11
Proteins containing Ly6/uPAR (LU) domains exhibit very diverse biological functions and have broad taxonomic distributions in eukaryotes. In general, they adopt a characteristic three-fingered folding topology with three long loops projecting from a disulfide-rich globular core. The majority of the members of this protein domain family contain only a single LU domain, which can be secreted, glycolipid anchored, or constitute the extracellular ligand binding domain of type-I membrane proteins. No ...[more]