Adherence and Tolerability of Alzheimer's Disease Medications: A Pragmatic Randomized Trial.

ABSTRACT:

Background/objectives

Post-marketing comparative trials describe medication use patterns in diverse, real-world populations. Our objective was to determine if differences in rates of adherence and tolerability exist among new users to acetylcholinesterase inhibitors (AChEI's).

Design

Pragmatic randomized, open label comparative trial of AChEI's currently available in the United States.

Setting

Four memory care practices within four healthcare systems in the greater Indianapolis area.

Participants

Eligibility criteria included older adults with a diagnosis of possible or probable Alzheimer's disease (AD) who were initiating treatment with an AChEI. Participants were required to have a caregiver to complete assessments, access to a telephone, and be able to under

SUBMITTER: Campbell NL 

PROVIDER: S-EPMC6604617 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature