Ontology highlight
ABSTRACT:
SUBMITTER: Sateriale A
PROVIDER: S-EPMC6617386 | biostudies-literature | 2019 Jul
REPOSITORIES: biostudies-literature
Sateriale Adam A Šlapeta Jan J Baptista Rodrigo R Engiles Julie B JB Gullicksrud Jodi A JA Herbert Gillian T GT Brooks Carrie F CF Kugler Emily M EM Kissinger Jessica C JC Hunter Christopher A CA Striepen Boris B
Cell host & microbe 20190620 1
Cryptosporidium is a leading cause of diarrheal disease and an important contributor to early childhood mortality, malnutrition, and growth faltering. Older children in high endemicity regions appear resistant to infection, while previously unexposed adults remain susceptible. Experimental studies in humans and animals support the development of disease resistance, but we do not understand the mechanisms that underlie protective immunity to Cryptosporidium. Here, we derive an in vivo model of Cr ...[more]