Evaluation of the Number-Needed-to-Biopsy Metric for the Diagnosis of Cutaneous Melanoma: A Systematic Review and Meta-analysis.

ABSTRACT:

Importance

To date, no concerted effort has been made to date to evaluate the literature on number-needed-to-biopsy (NNB) metrics, particularly to account for the differences in clinician type and melanoma prevalence in certain geographic locations.

Objective

To review and synthesize worldwide data for NNB for the diagnosis of cutaneous melanoma.

Data source

MEDLINE, Embase, and PubMed databases were searched for English-language articles published worldwide from January 1, 2000, to November 28, 2018.

Study selection

A total of 46 studies were included that addressed NNB for at least 3681 clinicians worldwide and included 455 496 biopsied tumors and 29 257 melanomas; primary care practitioner (PCP) data were only available from Australia.

Data extraction and

SUBMITTER: Nelson KC 

PROVIDER: S-EPMC6624799 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature