Ontology highlight
ABSTRACT:
SUBMITTER: Huang WY
PROVIDER: S-EPMC6640993 | biostudies-literature | 2017 Feb
REPOSITORIES: biostudies-literature
ACS omega 20170210 2
We describe a cascade Wacker/allylation sequence of β-hydroxy ynones by directly using simple allylic alcohols. This palladium(II)-catalyzed reaction occurs under mild conditions (0 °C to room temperature) and provides a new and efficient synthetic method for the preparation of allylated dihydropyrones. The regiochemical outcomes are consistent with a reaction pathway that includes an insertion/β-OH elimination sequence to form the allylic moiety. A remarkable changeover from allyl to formylethy ...[more]