Antimicrobial activity of novel synthesized coumarin based transitional metal complexes.

ABSTRACT:

Objectives

To synthesize new transitional metal complexes derived from 3-aryl-azo-4-hydroxy coumarin analogues and to evaluate their antimicrobial activities.

Methods

The syntheses of complexes of coumarin analogues were accomplished by mixing a hydro-alcoholic solution of 3-aryl-azo-4-hydroxy coumarin analogues with transition metal chlorides. The structural environment of the synthesized molecules was characterized using different instrumental methods. The antimicrobial activity of the compounds was determined by the agar well diffusion method.

Results

The cobalt complexes of (E)-3-((4-chlorophenyl) diazenyl)-4-hydroxy-2H-chromen-2-one (HL₁): (4a) and (E)-3-((4-methoxyphenyl) diazenyl)-4-hydroxy-2H-chromen-2-one (HL₂): (

SUBMITTER: Sahoo J 

PROVIDER: S-EPMC6694993 | biostudies-literature | 2017 Apr

REPOSITORIES: biostudies-literature