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The MaCreA Gene Regulates Normal Conidiation and Microcycle Conidiation in Metarhizium acridum.


ABSTRACT: As a C2H2 type zinc finger transcription factor, CreA is the key in Carbon Catabolism Repression (CCR) pathway, which negatively regulates the genes in carbon sources utilization. As conidiation in filamentous fungi is affected by nutritional conditions, CreA may contribute to fungal conidiation, which has been well studied in filamentous fungi, especially Aspergillus spp., but researches on entomopathogenic fungi are not enough. In this study, we found a homologous gene MaCreA in Metarhizium acridum, and the MaCreA deletion strain showed delayed conidiation, significant decrease in conidial yield, and 96.88% lower conidial production, when compared with the wild-type strain, and the normal conidiation and microcycle conidiati

SUBMITTER: Song D 

PROVIDER: S-EPMC6713048 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature