Serum Levels of Soluble Urokinase Plasminogen Activator Receptor in Infants with Late-onset Sepsis.

ABSTRACT:

Background

Soluble urokinase plasminogen activator receptor (suPAR) has been studied in a variety of diseases. The aim of the study is to investigate the levels of suPAR in neonates with sepsis.

Methods

The infants enrolled to this prospective study were classified into four groups. Group 1, 2, and 3 were referred as the patient groups (40 infants), and group 4 was referred as control group (26 infants). Blood samples for whole blood count, C-reactive protein (CRP), suPAR and blood culture were obtained before initiating antimicrobial therapy, and two further samples were obtained on day 3 and at the end of the treatment for CRP and suPAR.

Results

The mean gestational ages of patient and control groups was similar. The median level of initial suPAR was 18.8 ng/mL (ran

SUBMITTER: Okulu E 

PROVIDER: S-EPMC6806707 | biostudies-literature | 2015 Sep

REPOSITORIES: biostudies-literature