Effect of diabetes mellitus on risk of latent TB infection in a high TB incidence area: a community-based study in Taiwan.

ABSTRACT:

Objective

To investigate the association between diabetes and latent tuberculosis infections (LTBI) in high TB incidence areas.

Design

Community-based comparison study.

Setting

Outpatient diabetes clinics at 4 hospitals and 13 health centres in urban and rural townships. A community-based screening programme was used to recruit non-diabetic participants.

Participants

A total of 2948 patients with diabetes aged older than 40 years were recruited, and 453 non-diabetic participants from the community were enrolled.

Primary and secondary outcome measures

The interferon-gamma release assay (IGRA) and the tuberculin skin test were used to detect LTBI. The IGRA result was used as a surrogate of LTBI in logistic regression analysis.

Results

Diabetes was s

SUBMITTER: Lin CH 

PROVIDER: S-EPMC6830704 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature