Reference equations for spirometry in healthy Asian children aged 5 to 18 years in Taiwan.

ABSTRACT:

Background and objective

This study aimed to establish reference equations for spirometry in healthy Taiwanese children and assess the applicability of the Global Lung Function Initiative (GLI)-2012 equations to Taiwanese children.

Methods

Spirometric data collected from 757 healthy Taiwanese children aged 5 to 18 years in a population-based cohort study. Prediction equations derived using linear regression and the generalized additive models for location, scale and shape (GAMLSS) method, respectively.

Results

The GLI-2012 South East Asian equations did not provide a close fit with mean ± standard error z-scores of -0.679 ± 0.030 (FVC), -0.186 ± 0.044 (FEV₁), -0.875 ± 0.049 (FEV₁/FVC ratio) and -2.189 ± 0.063 (FEF_25-75) for girl

SUBMITTER: Chang SM 

PROVIDER: S-EPMC6835053 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature