Macular corneal dystrophy with isolated peripheral Descemet membrane deposits.

ABSTRACT:

Purpose

Macular Corneal Dystrophy (MCD, MIM #217800) is a category 1 corneal stromal dystrophy as per the current IC3D classification. While characterized by macular stromal deposits, we report a case of MCD type II with isolated bilateral peripheral Decemet membrane opacities, describing the clinical features and results of screening the CHST6 gene and serum sulfated keratan sulfate levels.

Observations

A 68-year-old man with an unremarkable past medical and family history presented with bilateral progressive decrease in vision. Ocular exam revealed bilateral clear corneas with the exception of peripheral, round, gray-white discrete deposits at the level of Descemet membrane and decreased central corneal thickness in both eyes. The morphology of the corneal deposits,

SUBMITTER: Zhang W 

PROVIDER: S-EPMC6881691 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature