A pilot study to examine the association between human gut microbiota and the host's central obesity.

ABSTRACT:

Background and aim

Perturbance in the composition of human gut microbiota has been associated with metabolic disorders such as obesity, diabetes mellitus, and insulin resistance. The objectives of this study are to examine the effects of ethnicity, central obesity, and recorded dietary components on potentially influencing the human gut microbiome. We hypothesize that these factors have an influence on the composition of the gut microbiome.

Methods

Subjects of Chinese (n = 14), Malay (n = 10), and Indian (n = 11) ancestry, with a median age of 39 years (range: 22-70 years old), provided stool samples for gut microbiome profiling using 16S rRNA sequencing and completed a dietary questionnaire. The serum samples were assayed for a panel of biomarkers (inte

SUBMITTER: Koo SH 

PROVIDER: S-EPMC6891071 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature