Molecular effects of Moringa leaf extract on insulin resistance and reproductive function in hyperinsulinemic male rats.

ABSTRACT:

Background

Many studies have reported that insulin resistance impairs the antioxidant defense system and causes male infertility. Moringa oleifera is a medicinal plant that has been employed for the medicament of many disorders. It controls the levels of glucose and manages male sexual disorders. However, its extracts can reverse insulin resistance-linked metabolic alterations remains unknown. Therefore, the current study investigated the potential of the aqueous leaves extract from Moringa oleifera to reverse insulin resistance and testicular disorders in rats.

Methods

Rats were fed either a chow (as a control group) or a high fructose diet (HFD, to persuade a state of insulin resistance), in addition to a group of rats fed HFD and treated with Moringa

SUBMITTER: Mohamed MA 

PROVIDER: S-EPMC6915189 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature