Sequence analysis of mitochondrial cytochrome c oxidase 1 and cytochrome b genes of echinococcus multilocularis from human patients.

ABSTRACT: Echinococcus multilocularis (E. multilocularis) is the cause of alveolar echinococcosis (AE) in humans. Differences in gene sequence may exist among strains of E. multilocularis that are isolated from different patients in different areas of Xinjiang Uyghur Autonomous Region of China. Other studies have shown that genetic variation and biomolecular classification of E. multilocularis exists. A total of 47 AE samples were collected from AE patients for sequence analysis of mitochondrial cytochrome c oxidase 1 (cox1) and cytochrome b (cytb) genes using PCR. We compared the obtained sequences with the GenBank database to identify the parasite and 5 haplotypes were detected among the geographical isolates from cox1 and cytb, respectively. Nearly all of the samples originated from Northern Xinj

SUBMITTER: Abulizi A 

PROVIDER: S-EPMC6958033 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature